# Mesothelioma

  **Table of Contents**

 **Table of Contents** [Overview](#section-overview "Overview") [Signs & Symptoms](#section-5091 "Signs & Symptoms") [Risk Factors](#section-5096 "Risk Factors") [Additional Factors That May Increase Risk](#section-8626 "Additional Factors That May Increase Risk") [Treatments & Services](#section-8636 "Treatments & Services") [Find Care](#section-5101 "Find Care") [Request an Appointment](#section-8656 "Request an Appointment")

## Overview

Mesothelioma is a rare and aggressive cancer that develops in the mesothelium, the thin protective lining that covers many of the body's internal organs. It most often forms in the tissue surrounding the lungs, known as the pleura, which is called pleural mesothelioma. Less commonly, it can occur in the lining of the abdomen (peritoneal mesothelioma) or, very rarely, around the heart or testicles.

Although treatment options continue to advance, mesothelioma is often diagnosed at a later stage and can be challenging to cure. Early evaluation and a coordinated care approach are important for managing symptoms, improving quality of life, and determining the most effective treatment plan.

## Signs & Symptoms

Mesothelioma symptoms often develop slowly and can vary based on where the cancer forms. Because early signs may resemble other common conditions, it is important to talk with a doctor if symptoms persist or worsen.

**Pleural Mesothelioma (lining around the lungs)****Peritoneal Mesothelioma (lining of the abdomen)**Chest discomfort or tightnessAbdominal pain or crampingPersistent or painful coughAbdominal swelling or fluid buildupShortness of breathNausea or changes in appetiteUnusual lumps or thickening under the skin of the chestUnexplained weight lossUnexplained weight loss or fatigue **Other Rare Types of Mesothelioma**

Pericardial mesothelioma, which affects the lining around the heart, may cause chest pain, irregular heartbeat, or trouble breathing.

Mesothelioma of the tunica vaginalis, which forms around the testicles, is often first noticed as swelling or a painless mass in the scrotum.

If you notice ongoing or unusual symptoms in any of these areas, reach out to your doctor for evaluation.

## Risk Factors

Mesothelioma is most closely linked to asbestos exposure, but several factors can influence a person's overall risk. Not everyone exposed to asbestos will develop mesothelioma, which suggests that genetics and other health factors also play a role.

**Asbestos Exposure (Primary Risk Factor)**

Asbestos is a naturally occurring mineral once widely used in construction, insulation, automotive parts, and industrial materials. When asbestos-containing products are disturbed, tiny fibers can become airborne. If inhaled or swallowed, these fibers can lodge in the lining of the lungs or abdomen, causing long-term irritation that may lead to mesothelioma decades later.

Mesothelioma often develops 20 to 60 years after exposure, making it one of the longest latency periods of any cancer.

## Additional Factors That May Increase Risk

While asbestos exposure remains the most significant factor, mesothelioma can occur in people without a known exposure history, highlighting the importance of early evaluation for persistent symptoms.

#####  Direct occupational or environmental exposure

Working in industries such as construction, shipbuilding, mining, or manufacturing increases the likelihood of asbestos exposure.

#####  Secondhand exposure

Being around someone who works with asbestos can also be a risk. Asbestos fibers may be carried home on clothing, skin, or hair, exposing family members over time.

#####  Family history of mesothelioma

A close relative with mesothelioma may indicate a hereditary susceptibility that raises your personal risk.

#####  Prior chest radiation

Radiation therapy to the chest for other cancers may slightly increase the risk of developing mesothelioma later in life.

## Treatments & Services

 Treatment Options

Treatment for mesothelioma focuses on controlling disease growth, managing symptoms, and improving quality of life. The right approach depends on the type of mesothelioma, how far it has spread, and your overall health. Many patients receive a combination of therapies delivered by a multidisciplinary team experienced in treating this rare disease.

[Chemotherapy](/all-treatments-services/chemotherapy)

[Immunotherapy](/all-treatments-services/immunotherapy)

[Radiation Therapy](/all-treatments-services/radiation-therapy)

[Surgical Oncology](/all-treatments-services/surgical-oncology)

[Targeted Therapy](/all-treatments-services/targeted-therapy)

## Find Care

If you or a loved one has been diagnosed with mesothelioma, expert care matters. Our multidisciplinary team includes specialists in medical oncology, thoracic surgery, radiation therapy, and supportive care, all working together to design a treatment plan tailored to your diagnosis and needs.

Our Locations

We offer locations across the DFW metroplex so you can receive leading cancer care and support close to home.

 [Find a Location](/locations)

Our Care Team

Get to know the compassionate experts who guide your care with a whole-person approach—spirit, mind, and body.

 [Meet Our Team](/our-care-team)

## Request an Appointment

Contact us to request an appointment or ask a question below. **For emergencies call 911 or visit your nearest hospital.**

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