The Center Insights

Living with Multiple Myeloma: What Patients and Families Should Know

1 min read March 24, 2026

Overview

Living with multiple myeloma can be physically and emotionally challenging, but understanding the disease and available treatments can help patients and families navigate the journey with more confidence and support.

What Is Multiple Myeloma?

Multiple myeloma is a type of blood cancer that forms in plasma cells, a kind of white blood cell found in the bone marrow that helps the body fight infections. In myeloma, these cells become cancerous and crowd out healthy blood cells, leading to symptoms like fatigue, bone pain, and increased risk of infection.

Unlike other cancers, multiple myeloma is often chronic, meaning it may not be curable but can often be managed over time with treatment.

Common Symptoms

Myeloma can affect different parts of the body and cause a variety of symptoms, including:

  • Bone pain or fractures (especially in the back, ribs, or hips)
  • Fatigue or weakness
  • Frequent infections
  • High calcium levels
  • Kidney dysfunction 
  • Weight loss or appetite changes

Talk to your doctor if you're experiencing persistent or unexplained symptoms.

Risk Factors and Diagnosis

Multiple myeloma most often affects people over age 65, and it's more common in men and in African American populations. Other risk factors include:

  • A personal history of monoclonal gammopathy of undetermined significance (MGUC)
  • Family history of myeloma
  • Obesity or long-term exposure to certain chemicals like pesticides or radiation

Diagnosis typically involves blood tests, urine tests, bone marrow biopsy, and imaging studies (X-rays, CT scans, or MRIs).

Treatment Options

Treatment is highly individualized and may include:

  • Targeted therapy
  • Immunotherapy
  • Chemotherapy
  • CAR-T Cell Therapy
  • Corticosteroids 
  • Stem cell transplant (often after initial treatment to prolong remission)

New therapies are emerging that offer hope for longer remission periods and improved quality of life. Many patients live for years with myeloma, especially with early diagnosis, newer treatments, and strong care teams.

Living with Myeloma

Myeloma is a complex disease that requires ongoing monitoring and lifestyle support. 

Patients and caregivers should prioritize:

  • Regular follow-ups with their oncology team
  • Managing side effects like fatigue and bone loss
  • Infection prevention strategies
  • Mental and emotional well-being
  • Support groups and education resources

You are not alone. There are resources, treatments, and communities ready to walk alongside you.