All Cancers & Diseases

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Cancers & Diseases Lymphoma

Lymphoma is a type of blood cancer that affects the lymphatic system, a vital part of the immune system that helps protect the body from infection and disease. The lymphatic system includes the lymph nodes, spleen, thymus, and bone marrow.Lymphoma develops when lymphocytes, a type of white blood cell, begin to grow and multiply abnormally. These cells live longer than they should, which can crowd out healthy immune cells and weaken the body's ability to fight infection.There are two main types of lymphoma:Non-Hodgkin lymphoma (NHL)Hodgkin lymphoma (formerly called Hodgkin disease)The main difference between the two is the type of lymphocyte involved. Hodgkin lymphoma is defined by the presence of Reed-Sternberg cells, a specific type of abnormal B cell seen under a microscope. Non-Hodgkin lymphoma includes a broader group of blood cancers that can start in B cells or T cells and often behave differently in how quickly they grow or respond to treatment.

Cancers & Diseases Mesothelioma

Mesothelioma is a rare and aggressive cancer that develops in the mesothelium, the thin protective lining that covers many of the body's internal organs. It most often forms in the tissue surrounding the lungs, known as the pleura, which is called pleural mesothelioma. Less commonly, it can occur in the lining of the abdomen (peritoneal mesothelioma) or, very rarely, around the heart or testicles.Although treatment options continue to advance, mesothelioma is often diagnosed at a later stage and can be challenging to cure. Early evaluation and a coordinated care approach are important for managing symptoms, improving quality of life, and determining the most effective treatment plan.

Cancers & Diseases Myeloma

Myeloma, most often referred to as multiple myeloma, is an uncommon type of blood cancer that begins in plasma cells, a form of white blood cell found in the bone marrow. Plasma cells normally produce antibodies that help the body fight infection, but in multiple myeloma, abnormal plasma cells grow uncontrollably and crowd out healthy blood cells. These malignant cells often produce an abnormal antibody called M protein, which is a hallmark of the disease and can contribute to kidney problems and other complications. This disruption can lead to bone damage, anemia, and a weakened immune system.As myeloma progresses, abnormal plasma cells may form tumors within the bones, causing pain, fractures, or other complications.

Cancers & Diseases Oral Cancer

Oral cancer is a type of head and neck cancer that develops in the tissues of the mouth. It can form on the lips, tongue, gums, inner cheeks, the roof or floor of the mouth, or the area just behind the wisdom teeth. While oral cancer can affect anyone, it is more common in people who use tobacco or alcohol, have prolonged sun exposure to the lips, or have certain viral infections such as HPV.Early detection significantly improves outcomes, but oral cancer is often found at a later stage because early changes can be subtle. Regular dental checkups, self-exams, and prompt evaluation of any new or persistent changes in the mouth are important steps in catching oral cancer early.

Cancers & Diseases Osteoarthritis

Osteoarthritis is the most common type of arthritis and occurs when the cartilage that cushions the ends of the bones gradually wears down. This protective cartilage helps joints move smoothly, so when it becomes thinner or damaged, bones can rub against each other and cause pain, stiffness, and swelling.Osteoarthritis can affect any joint, but it most often involves the hands, knees, hips, and spine. Symptoms tend to develop slowly and may worsen over time.While joint damage cannot be reversed, many people are able to effectively manage symptoms. Staying active, maintaining a healthy weight, and working with your care team to explore treatment options can help reduce pain, improve mobility, and support long-term joint function.If joint pain from osteoarthritis is making daily activities more difficult, there are safe and proven treatment options beyond medication and injections. Low-Dose Radiation Therapy (LD-RT) is a noninvasive approach that targets inflammation and helps reduce pain without surgery or downtime.

Cancers & Diseases Ovarian Cancer

Ovarian cancer begins when abnormal cells in the ovaries grow and divide more quickly than they should, forming a tumor that can spread to nearby tissues or other areas of the body. The ovaries are two small, almond-shaped organs located on each side of the uterus. They produce eggs as well as the hormones estrogen and progesterone.Ovarian cancer can be challenging to detect early because symptoms are often subtle or mistaken for other conditions. When it is found at an early stage, outcomes are significantly more favorable. Treatment usually includes surgery, chemotherapy, and other targeted approaches depending on the specific type and stage of disease.

Cancers & Diseases Pancreatic Cancer

Pancreatic cancer begins in the pancreas, an organ behind the stomach that helps with digestion and blood sugar regulation. Most cases start in the ductal cells that carry digestive enzymes out of the pancreas, known as pancreatic ductal adenocarcinoma.Because early pancreatic cancer rarely causes symptoms, it is often diagnosed at a later stage. When detected, treatment depends on the cancer's location and extent and may include surgery, chemotherapy, radiation therapy, or a combination of these options.

Cancers & Diseases Penile Cancer

Penile cancer is a rare disease that begins in the skin or tissues of the penis. Most cases start in the cells that line the skin of the penis and may first appear as subtle skin changes that can easily be mistaken for benign conditions. Early detection is very important, since penile cancer is most treatable in its earliest stages. Penile cancer is not infectious and does not run in families.

Cancers & Diseases Primary Peritoneal Cancer

Primary peritoneal cancer is a rare cancer that starts in the peritoneum, the thin membrane that lines the inside of the abdomen and covers organs like the stomach, liver, and intestines. Because the peritoneum and the surface of the ovaries are made of the same type of cells, this cancer closely resembles epithelial ovarian cancer and is treated the same way. It occurs almost exclusively in women, is more common as people age, and is often diagnosed after ovarian cancer has been ruled out. A separate and less common cancer that affects this lining is peritoneal mesothelioma, which is typically linked to asbestos exposure.

Cancers & Diseases Prostate Cancer

Prostate cancer begins in the prostate, a small gland below the bladder that produces seminal fluid. It is one of the most common cancers in men, especially those over age 50. Many prostate cancers grow slowly and remain confined to the gland, while others are more aggressive and can spread to nearby tissues or distant parts of the body.Because early prostate cancer often causes no symptoms, many cases are found during routine screening or evaluation for other urinary concerns. When detected early and still limited to the prostate, prostate cancer is highly treatable. Understanding the type and growth pattern of the cancer helps guide the best approach to care.

News, Events , & Media

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The Center Insights Men's Health and Cancer: Screenings Every Man Should Know

Men's health and cancer screenings play an important role in detecting cancer early, when treatment is often most effective. Regular screenings can help identify cancer before symptoms develop, allowing for earlier diagnosis and better outcomes.During Men's Health Month, it is important for men to understand which cancer screenings may be recommended based on age, risk factors, and personal health history. Speaking with a healthcare provider about screening options can help ensure that the right preventative steps are taken.Routine screenings are one of the most effective ways to detect certain cancers early and improve survival rates. 

Published Date: June 10, 2026

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The Center Insights Understanding Cancer Survivorship: Life After Treatment

Cancer survivorship begins at the time of a cancer diagnosis and continues throughout the rest of a person's life. While completing treatment is an important milestone, many patients find that life after cancer comes with new questions, challenges, and adjustments.During National Cancer Survivors Month, it is important to recognize that survivorship includes physical recovery, emotional well-being, and ongoing medical care. With the right support and follow-up care, many cancer survivors are able to return to daily activities and focus on long-term health.According to the National Cancer Institute, there are millions of cancer survivors in the United States, highlighting the importance of survivorship care and support.

Published Date: June 1, 2026

COA logo with text: Patients experience longer survival in community oncology settings
Press Release Cancer Patients Experience Longer Survival In Community Oncology Settings

Flatiron Health and Community Oncology Alliance partner to deliver first comprehensive, real-world assessment of care in community oncology, affirming the high-quality care delivered across community practices.Patients diagnosed with metastatic breast cancer and non-small cell lung cancer had longer survival compared to national benchmarks when treated in independent community oncology practices, according to a new study commissioned by the Community Oncology Alliance (COA) and conducted by Flatiron Health. The research supports independent community oncologists' ability to deliver high-quality outcomes for the majority of U.S. patients with cancer who receive care in community oncology settings.The study shows that median survival for patients diagnosed with breast cancer that spread to other organs and treated at a Flatiron Health Research Network (FHRN) community oncology practice exceeded national benchmarks by eight months. Median survival for those with non-small cell lung cancer- the most common lung cancer- treated at FHRN community oncology practices exceeded national benchmarks by two month. Survival rates after one, three, and five years were consistently higher for patients treated at community oncology practices within the FHRN relative to national benchmarks.Click to read the full press releaseClick to read the full study on quality of care in community oncology

Published Date: May 20, 2026