Clinical Trials & Research

Advancing Care Through Innovation and Research

Since 1998, under the research leadership of Dr. Ray Page, our practice has participated in nearly 200 clinical trials involving more than 60 experimental drugs, many of which have since earned FDA approval and are now used as standard of care treatments. Our physicians have become recognized leaders in the use of novel cancer agents, and hundreds of patients have already benefited from these groundbreaking research efforts.

Offering clinical trials reflects the highest standard of excellence in both clinical care and comprehensive patient management. Every member of our team, physicians to research staff, receive specialized training to uphold the strictest standards of good clinical practice as we safely administer experimental drugs and therapies.

What Clinical Trials May Involve

Clinical trials can study:

• New cancer medications
• Immunotherapy or targeted therapy combinations
• Chemotherapy delivered in new ways
• Radiation approaches or surgical techniques
• Supportive care methods to improve comfort or quality of life
• Diagnostic tests or genetic profiling
• Improve existing treatments
• Advance personalized medicine through biomarker driven studies
• Evaluate preventative strategies and early detection methods 

Each trial has specific goals and eligibility requirements to ensure safety and meaningful results.

Trial Phases

Phase 1: Safety First

This is the first time a new treatment is tested in people. Researchers start with very low doses to find out:

• What dose is safe
• How the body reacts
• What side effects may occur

The goal is to find the highest dose that’s still safe.

Phase 2: Does it Work

Once safety is established, Phase 2 trials test whether the treatment works. Researchers look at:

• How well the treatment fights cancer
• Continued monitoring of side effects

Phase 3: Comparing Treatments

The new treatment is compared to the current standard of treatment. This phase includes:

• A large group of patients
• Detailed tracking of effectiveness and side effects
• Long-term outcome data

Sometimes phase 2 & 3 are combined.

Phase 4: Real World Results

After a treatment is approved, Phase 4 trials continue to monitor it in everyday use. THese studies help researchers understand:

• Long-term benefits and risks
• How the treatment works in a wide range of patients
• Potential new uses or combinations

Why Patients Consider Clinical Trials

Many patients explore clinical trial options to learn whether new or emerging treatments may be right for them. A trial may offer access to medications or therapy combinations that are not yet widely available, or it may help determine whether a targeted treatment matches the genetic features of their tumor. Patients often appreciate the added monitoring and support that comes with participating in a study, as well as the opportunity to contribute to research that may improve cancer care for others in the future. 

Participation in a clinical trial is always voluntary, and patients may choose to withdraw from a study at any time.

Who May Be Eligible

Eligibility varies by study but may include patients who:

• Are newly diagnosed
• Have cancer that has returned or progressed
• Have cancers with specific genetic or molecular features
• Have not responded to standard treatments
• Want access to new or innovative options

Your oncologist or research team will explain which studies are available and whether any may be a good fit for you.

Clinical Trials

OneR - https://www.oneoncology.com/one-r/
START Research - https://startresearch.com/